Depo-Provera lawsuits involve legal claims brought by women who experienced serious health complications after using Depo-Provera, a contraceptive injection designed to prevent pregnancy for up to three months per dose. While many women use the medication safely, a growing number of plaintiffs allege that Depo-Provera can cause severe side effects, including bone density loss, osteoporosis, blood clots, cardiovascular complications, infertility, and abnormal menstrual changes, some of which can be long-term or permanent.

The lawsuits focus on claims that the manufacturer, Pfizer (and previously Upjohn), failed to adequately warn patients and healthcare providers about these serious risks. Plaintiffs allege that despite years of research highlighting potential complications, warnings on labeling and promotional materials were insufficient or misleading, leaving patients unaware of the potential for lasting harm.

Many Depo-Provera lawsuits involve personal injury claims, where affected women seek compensation for medical expenses, pain and suffering, future healthcare needs, and the emotional impact of injuries caused by the drug. Some cases also allege long-term reproductive harm, including difficulties with fertility after discontinuing the medication.

Because these lawsuits involve similar claims and scientific evidence, multiple cases have been centralized in multidistrict litigation (MDL) or coordinated pretrial proceedings in federal court. This process helps manage discovery, expert testimony, and legal strategy across many cases while ensuring consistent rulings on key issues such as product warnings, causation, and manufacturer responsibility.

The manufacturers of Depo-Provera maintain that the drug is safe when used as prescribed and that known side effects are included in the labeling. However, plaintiffs’ attorneys argue that the severity and likelihood of certain adverse effects were downplayed, leaving patients vulnerable to serious health problems without full knowledge of the risks.

Depo-Provera lawsuits are ongoing and represent a significant area of pharmaceutical product liability litigation. For women who have suffered serious complications after receiving the contraceptive injection, these lawsuits provide a pathway to seek accountability, compensation for medical care, and redress for long-term health consequences.